Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | activation-induced deaminase is present in a complex containing the regulatory subunit Ialpha and, possibly, the catalytic subunit of protein kinase A in the cytoplasm of B cells, suggesting that protein kinase A itself may contribute in part to the localization of AID in this compartment | Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cytosine in single-stranded DNA + H2O | Homo sapiens | - |
uracil in single-stranded DNA + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9GZX7 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | protein kinase A phosphorylates activation-induced cytidine deaminase and regulates its activity in GC B cells. Phosphorylation targets specifically Thr27 and Ser38 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
B-lymphocyte | germinal center B-cell | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cytosine in single-stranded DNA + H2O | - |
Homo sapiens | uracil in single-stranded DNA + NH3 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
activation-induced deaminase | - |
Homo sapiens |
AID | - |
Homo sapiens |