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Literature summary for 3.5.4.38 extracted from

  • Yang, G.; Obiakor, H.; Sinha, R.K.; Newman, B.A.; Hood, B.L.; Conrads, T.P.; Veenstra, T.D.; Mage, R.G.
    Activation-induced deaminase cloning, localization, and protein extraction from young VH-mutant rabbit appendix (2005), Proc. Natl. Acad. Sci. USA, 102, 17083-17088.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.4.38

Cloned(Commentary)

Cloned (Comment) Organism
-
 Oryctolagus cuniculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26000
-
 2 * 26000, SDS-PAGE Oryctolagus cuniculus
26000
-
 1 * 26000, SDS-PAGE Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytosine in single-stranded DNA + H2O Oryctolagus cuniculus activation-induced deaminase (AID) is involved in processes leading to antibody diversification: somatic hypermutation, gene conversion, and class-switch recombination uracil in single-stranded DNA + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Oryctolagus cuniculus Q3BAF8
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Oryctolagus cuniculus

Source Tissue

Source Tissue Comment Organism Textmining
vermiform appendix
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytosine in single-stranded DNA + H2O
-
 Oryctolagus cuniculus uracil in single-stranded DNA + NH3
-
 ?
cytosine in single-stranded DNA + H2O activation-induced deaminase (AID) is involved in processes leading to antibody diversification: somatic hypermutation, gene conversion, and class-switch recombination Oryctolagus cuniculus uracil in single-stranded DNA + NH3
-
 ?

Subunits

Subunits Comment Organism
dimer 2 * 26000, SDS-PAGE Oryctolagus cuniculus
monomer 1 * 26000, SDS-PAGE Oryctolagus cuniculus

Synonyms

Synonyms Comment Organism
activation-induced cytidine deaminase
-
 Oryctolagus cuniculus
AICDA
-
 Oryctolagus cuniculus
AID
-
 Oryctolagus cuniculus

General Information

General Information Comment Organism
physiological function activation-induced deaminase (AID) is involved in processes leading to antibody diversification: somatic hypermutation, gene conversion, and class-switch recombination Oryctolagus cuniculus