Cloned (Comment) | Organism |
---|---|
- |
Pleurodeles waltl |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
additional information | - |
activation-induced cytidine deaminase mRNA is not alternatively spliced in Pleurodeles waltl | Pleurodeles waltl |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Pleurodeles waltl | activation-induced cytidine deaminase is function in Pleurodeles waltl. The lack of class switch recombination activity in Pleurodeles waltl is therefore not due to a defect in expression or function of activation-induced cytidine deaminase | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pleurodeles waltl | D5GRW1 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
spleen | predominantly expressed in the spleen. The enzyme is expressed early during embryonic development of Pleurodeles waltl | Pleurodeles waltl | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | activation-induced cytidine deaminase is function in Pleurodeles waltl. The lack of class switch recombination activity in Pleurodeles waltl is therefore not due to a defect in expression or function of activation-induced cytidine deaminase | Pleurodeles waltl | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
activation-induced cytidine deaminase | - |
Pleurodeles waltl |
AID | - |
Pleurodeles waltl |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in immunoglobulin affinity maturation, gene conversion and class switch recombination. This protein is therefore a major actor in the creation of the antibody repertoire | Pleurodeles waltl |