Localization | Comment | Organism | GeneOntology No. | Textmining |
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Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | overexpression of p150 ADAR1 has no significant effect on the yield of vesicular stomatitis virus. reduction of p110 and p150 ADAR1 proteins to less than 10% to 15% of parental levels (ADAR1-deficient) has no significant effect on growth of Vesicular Stomatitis Virus in the absence of interferon treatment. The level of phosphorylated protein kinase PKR is increased in ADAR1-deficient cells compared to ADAR1-sufficient cells following IFN treatment, regardless of viral infection. ADAR1 suppresses activation of protein kinase PKR and inhibition of growth of Vesicular Stomatitis Virus in response to interferon treatment | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P55265 | P55265-1, isoform ADAR1 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | overexpression of p150 ADAR1 has no significant effect on the yield of vesicular stomatitis virus. reduction of p110 and p150 ADAR1 proteins to less than 10% to 15% of parental levels (ADAR1-deficient) has no significant effect on growth of Vesicular Stomatitis Virus in the absence of interferon treatment. The level of phosphorylated protein kinase PKR is increased in ADAR1-deficient cells compared to ADAR1-sufficient cells following IFN treatment, regardless of viral infection. ADAR1 suppresses activation of protein kinase PKR and inhibition of growth of Vesicular Stomatitis Virus in response to interferon treatment | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADAR1 | - |
Homo sapiens |