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Literature summary for 3.5.4.36 extracted from

  • Teng, B.; Burant, C.F.; Davidson, N.O.
    Molecular cloning of an apolipoprotein B messenger RNA editing protein (1994), Science, 260, 1816-1819.
    View publication on PubMed
Search for more literature for 3.5.4.36

Cloned(Commentary)

Cloned (Comment) Organism
when the catalytic subunit of the editing enzyme, p27, is expressed in Xenopus oocytes, it requires other proteins to edit apoB mRNA in vitro Rattus norvegicus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
27277
-
 x * 27277, calculated from sequence Rattus norvegicus
27280
-
 calculated from sequence Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytosine6666 in apolipoprotein B mRNA + H2O Rattus norvegicus mammalian apolipoprotein B (apo B) exists in two forms, each the product of a single gene. The shorter form, apo B48, arises by posttranscriptional RNA editing whereby cytidine deamination produces a UAA termination codon uracil6666 in apolipoprotein B mRNA + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus P38483
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colon
-
 Rattus norvegicus
-
small intestine
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytosine6666 in apolipoprotein B mRNA + H2O mammalian apolipoprotein B (apo B) exists in two forms, each the product of a single gene. The shorter form, apo B48, arises by posttranscriptional RNA editing whereby cytidine deamination produces a UAA termination codon Rattus norvegicus uracil6666 in apolipoprotein B mRNA + NH3
-
 ?

Subunits

Subunits Comment Organism
? x * 27277, calculated from sequence Rattus norvegicus

Synonyms

Synonyms Comment Organism
apo B messenger RNA editing protein
-
 Rattus norvegicus
REPR
-
 Rattus norvegicus