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Literature summary for 3.5.4.36 extracted from
- In vitro deamination of cytosine to uracil in single-stranded DNA by apolipoprotein B editing complex catalytic subunit 1 (APOBEC1) (2003), J. Biol. Chem., 278, 19583-19586.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | P38483 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cytosine in single-stranded DNA + H2O | when expressed in bacteria, APOBEC1 can deaminate cytosine in DNA. Its activity on DNA is specific for single-stranded DNA and exhibits dependence on local sequence context | Rattus norvegicus | uracil in single-stranded DNA + NH3 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| APOBEC1 | catalytic component of an RNA-editing complex | Rattus norvegicus |
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Release 2023.1 (January 2023)
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