Literature summary for 3.5.4.36 extracted from

Driscoll, D.M.; Zhang, Q.
Expression and characterization of p27, the catalytic subunit of the apolipoprotein B mRNA editing enzyme (1994), J. Biol. Chem., 269, 19843-19847.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of the catalytic subunit of the editing enzyme, p27, in McArdle 7777 cells and in in COS cells. Transfected COS and CHO cells express p27 but lack additional proteins that are required for editing	Rattus norvegicus

Protein Variants

Protein Variants	Comment	Organism
C96S	mutation abolishes activity	Rattus norvegicus
H61R	mutation abolishes activity	Rattus norvegicus
P92L	mutation abolishes activity	Rattus norvegicus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Zinc	the zinc finger in p27 may be required for catalysis, protein-protein interactions, or binding to apoB mRNA	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	P38483	-	-

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Release 2023.1 (January 2023)