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Literature summary for 3.5.4.34 extracted from

  • Keegan, L.P.; Gerber, A.P.; Brindle, J.; Leemans, R.; Gallo, A.; Keller, W.; O'Connell, M.A.
    The properties of a tRNA-specific adenosine deaminase from Drosophila melanogaster support an evolutionary link between pre-mRNA editing and tRNA modification (2000), Mol. Cell. Biol., 20, 825-833.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.4.34

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris Drosophila melanogaster

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45350
-
 x * 45350, calculated from sequence Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
adenine37 in tRNAAla + H2O Drosophila melanogaster
-
 hypoxanthine37 in tRNAAla + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster Q9V3R6
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenine37 in tRNAAla + H2O
-
 Drosophila melanogaster hypoxanthine37 in tRNAAla + NH3
-
 ?
adenine37 in tRNAAla + H2O the enzyme is specific for adenosine 37 of insect alanine tRNA, it has no activity on dsRNA substrates. Drosophila ADAT1 binds and deaminates tRNAAla from Bombyx mori 100fold more efficiently than the tRNAAla from Saccharomyces cerevisiae Drosophila melanogaster hypoxanthine37 in tRNAAla + NH3
-
 ?

Subunits

Subunits Comment Organism
? x * 45350, calculated from sequence Drosophila melanogaster

Synonyms

Synonyms Comment Organism
ADAT1
-
 Drosophila melanogaster