Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.4.31 extracted from

  • Hermann, J.C.; Marti-Arbona, R.; Fedorov, A.A.; Fedorov, E.; Almo, S.C.; Shoichet, B.K.; Raushel, F.M.
    Structure-based activity prediction for an enzyme of unknown function (2007), Nature, 448, 775-779.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.4.31

Cloned(Commentary)

Cloned (Comment) Organism
-
 Thermotoga maritima

Crystallization (Commentary)

Crystallization (Comment) Organism
X-ray crystal structure of the complex between Tm0936 and the product resulting from the deamination of SAH, S-inosylhomocysteine Thermotoga maritima

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.044
-
 S-methyl-5'-thioadenosine pH and temperature not specified in the publication Thermotoga maritima
0.25
-
 adenosine pH and temperature not specified in the publication Thermotoga maritima

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
S-methyl-5'-thioadenosine + H2O Thermotoga maritima
-
 S-methyl-5'-thioinosine + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Thermotoga maritima Q9X034
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Thermotoga maritima

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
adenosine + H2O
-
 Thermotoga maritima inosine + NH3
-
 ?
S-methyl-5'-thioadenosine + H2O
-
 Thermotoga maritima S-methyl-5'-thioinosine + NH3
-
 ?

Synonyms

Synonyms Comment Organism
5-methylthioadenosine deaminase
-
 Thermotoga maritima
5-methylthioadenosine/S-adenosylhomocysteine deaminase bifunctional enzyme EC 3.5.4.21/EC 3.5.4.28 Thermotoga maritima
MTA deaminase
-
 Thermotoga maritima
Tm0936
-
 Thermotoga maritima

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.3
-
 adenosine pH and temperature not specified in the publication Thermotoga maritima
7.2
-
 S-methyl-5'-thioadenosine pH and temperature not specified in the publication Thermotoga maritima

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
9.2
-
 adenosine pH and temperature not specified in the publication Thermotoga maritima
140
-
 S-methyl-5'-thioadenosine pH and temperature not specified in the publication Thermotoga maritima