General Stability | Organism |
---|---|
stable to heat | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5-aminoimidazole-4-carboxamide | - |
Homo sapiens | |
5-aminoimidazole-4-carboxamide | - |
Rattus norvegicus | |
Ag+ | 6.5% inhibition at 2 mM | Rattus norvegicus | |
Fe3+ | - |
Rattus norvegicus | |
Hg2+ | 98.6% inhibition at 2 mM | Rattus norvegicus | |
Li+ | - |
Rattus norvegicus | |
natural inhibitor protein | - |
Homo sapiens | |
natural inhibitor protein | - |
Mus musculus | |
natural inhibitor protein | heat labile proteinous mitochondrial inhibitor for liver and brain enzyme | Rattus norvegicus | |
Pb2+ | 55.5% inhibition at 2 mM | Rattus norvegicus | |
Zn2+ | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanine + H2O | Mus musculus | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Homo sapiens | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Rattus norvegicus | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Ophiodon elongatus | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Clostridium sp. | - |
xanthine + NH3 | - |
? | |
guanine + H2O | Rattus norvegicus Sprague Dawley | - |
xanthine + NH3 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridium sp. | - |
C. acidiurici | - |
Homo sapiens | - |
human | - |
Mus musculus | - |
mouse | - |
Ophiodon elongatus | - |
lingcod | - |
Rattus norvegicus | - |
Sprague Dawley strain | - |
Rattus norvegicus Sprague Dawley | - |
Sprague Dawley strain | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
brain | - |
Homo sapiens | - |
brain | - |
Rattus norvegicus | - |
kidney | - |
Homo sapiens | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Mus musculus | - |
liver | - |
Homo sapiens | - |
liver | - |
Rattus norvegicus | - |
lung | - |
Homo sapiens | - |
lung | - |
Rattus norvegicus | - |
muscle | - |
Homo sapiens | - |
muscle | - |
Ophiodon elongatus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.14 | - |
purified liver enzyme | Rattus norvegicus |
1.36 | - |
kidney enzyme | Rattus norvegicus |
9.9 | - |
liver enzyme, isoenzyme A | Rattus norvegicus |
13.2 | - |
brain enzyme | Rattus norvegicus |
23.5 | - |
lung enzyme | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
guanine + H2O | - |
Mus musculus | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Homo sapiens | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Rattus norvegicus | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Ophiodon elongatus | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Clostridium sp. | xanthine + NH3 | - |
? | |
guanine + H2O | - |
Rattus norvegicus Sprague Dawley | xanthine + NH3 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | - |
Homo sapiens |
dimer | - |
Rattus norvegicus |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
- |
80 | - |
Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
70 | - |
activity remains unaffected from 0-50°C, 19.3% inactivation at 60°C, 33% inactivation at 70°C, complete lost of activity at 80°C | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
- |
Rattus norvegicus |