Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'-IMP | competitive inhibition of deamination of adenosine 3'-phenylphosphonate | Todarodes pacificus | |
adenine | competitive inhibition of deamination of adenosine 3'-phenylphosphonate | Todarodes pacificus | |
Inosine | competitive inhibition of deamination of adenosine 3'-phenylphosphonate | Todarodes pacificus | |
purine riboside | competitive inhibition of deamination of adenosine 3'-phenylphosphonate | Todarodes pacificus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Todarodes pacificus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Todarodes pacificus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Todarodes pacificus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2',3'-cAMP + H2O | - |
Todarodes pacificus | 2',3'-cIMP + NH3 | - |
? | |
2'-deoxyadenosine + H2O | - |
Todarodes pacificus | 2'-deoxyinosine + NH3 | - |
? | |
3'-deoxyadenosine + H2O | - |
Todarodes pacificus | 3'-deoxyinosine + NH3 | - |
? | |
5'-deoxyadenosine + H2O | the enzyme shows much lower activity with 5'-deoxyadenosine than with 2'-deoxyadenosine or 3'-deoxyadenosine | Todarodes pacificus | 5'-deoxyinosine + NH3 | - |
? | |
adenosine + H2O | - |
Todarodes pacificus | inosine + NH3 | - |
? | |
adenosine 3'-phenyl phosphonate + H2O | - |
Todarodes pacificus | inosine 3'-phenylphosphonate + NH3 | - |
? | |
ApA + H2O | 37.6% of the activity with 2',3'-cAMP | Todarodes pacificus | IpI + NH3 | - |
? | |
ApC + H2O | 41.8% of the activity with 2',3'-cAMP | Todarodes pacificus | IpC + NH3 | - |
? | |
ApCpC + H2O | 12.1% of the activity with 2',3'-cAMP | Todarodes pacificus | IpCpC + NH3 | - |
? | |
ApG + H2O | 30.9% of the activity with 2',3'-cAMP | Todarodes pacificus | IpG + NH3 | - |
? | |
ApU + H2O | 51.5% of the activity with 2',3'-cAMP | Todarodes pacificus | IpU + NH3 | - |
? | |
additional information | the enzyme deaminates 5'-hydroxyl terminal adenosine residues in dinucleotides and trinucleotides, but not the 3'-hydroxyl terminal one in dinucleotides. The 5'-hydroxyl group of the ribose moiety is necessary for the substrate binding and catalytic activity of the squid enzyme | Todarodes pacificus | ? | - |
? |