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Literature summary for 3.5.4.16 extracted from

  • Kumar, S.; Sun, X.; Sharma, S.; Aggarwal, S.; Ravi, K.; Fineman, J.R.; Black, S.M.
    GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP (2009), Am. J. Physiol. Lung Cell Mol. Physiol., 297, L309-L317.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.4.16

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
lung
-
 Ovis aries
-
pulmonary artery endothelium
-
 Ovis aries
-

Synonyms

Synonyms Comment Organism
GCH1
-
 Ovis aries

Expression

Organism Comment Expression
Ovis aries exposure to the NO donor spermine NONOate (0-0.1 mM) leads to an dose-dependent increase in GCH1 protein. GCH1 promoter activity is enhanced by spermine NONOate in a CREB-dependent manner up

General Information

General Information Comment Organism
metabolism GTP cyclohydrolase I is the rate-limiting enzyme in generation of tetrahydrobiopterin Ovis aries