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Literature summary for 3.5.4.16 extracted from

  • Hatakeyama, K.; Harada, T.; Kagamiyama, H.
    IMP dehydrogenase inhibitors reduce intracellular tetrahydrobiopterin levels through reduction of intracellular GTP levels (1992), J. Biol. Chem., 267, 20734-20739.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
IMR-32 neuroblastoma cells
-
Rattus norvegicus
-
PC-12 pheochromocytoma cells
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
Homo sapiens
additional information
-
-
Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
Homo sapiens formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate
-
?
GTP + H2O
-
Rattus norvegicus formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate
-
?