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Literature summary for 3.5.4.12 extracted from

  • Gribaudo, G.; Riera, L.; Caposio, P.; Maley, F.; Landolfo, S.
    Human cytomegalovirus requires cellular deoxycytidylate deaminase for replication in quiescent cells (2003), J. Gen. Virol., 84, 1437-1441.
    View publication on PubMed
Search for more literature for 3.5.4.12

Activating Compound

Activating Compound Comment Organism Structure
additional information infection with the human cytomegalovirus upregulates the enzyme involved in thymidylate synthesis especially the dCMP deaminase, but not the dUTPase, overview Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
dCMP + H2O Homo sapiens the enzyme plays a key role in the thymidylate synthase, pathway overview dUMP + NH3
-
 ?
additional information Homo sapiens the human cytomegalovirus requires the cellular host dCMP deaminase for replication in quiescent cells, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HELF cell quiescent cells infected with human cytomegalovirus, HCMV Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
dCMP + H2O
-
 Homo sapiens dUMP + NH3
-
 ?
dCMP + H2O the enzyme plays a key role in the thymidylate synthase, pathway overview Homo sapiens dUMP + NH3
-
 ?
additional information the human cytomegalovirus requires the cellular host dCMP deaminase for replication in quiescent cells, overview Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
dCMP deaminase
-
 Homo sapiens
deoxycytidylate deaminase
-
 Homo sapiens