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Literature summary for 3.5.3.7 extracted from
- Degradation of 2-ketoarginine by guanidinobutyrase in arginine aminotransferase pathway of Brevibacterium helvolum (1995), Biosci. Biotechnol. Biochem., 59, 512-513.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| thioglycolate | - |
Brevibacterium helvolum |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 2.9 | - |
4-Guanidinobutyrate | - |
Brevibacterium helvolum | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-Guanidinobutyrate + H2O | Pimelobacter simplex | - |
4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | Brevibacterium linens | - |
4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | Arthrobacter globiformis | - |
4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | Streptomyces griseus | - |
4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | Brevibacterium helvolum | - |
4-Aminobutyrate + urea | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arthrobacter globiformis | - |
IFO 12137 (ATCC 8010) | - |
| Brevibacterium helvolum | - |
IFO 12073 (ATCC 11822) | - |
| Brevibacterium linens | - |
- |
- |
| Pimelobacter simplex | - |
- |
- |
| Streptomyces griseus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Brevibacterium helvolum |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 13 | - |
- |
Brevibacterium helvolum |
| 83.8 | - |
- |
Brevibacterium helvolum |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-Guanidinobutyrate + H2O | - |
Pimelobacter simplex | 4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | - |
Brevibacterium linens | 4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | - |
Arthrobacter globiformis | 4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | - |
Streptomyces griseus | 4-Aminobutyrate + urea | - |
? | |
| 4-Guanidinobutyrate + H2O | - |
Brevibacterium helvolum | 4-Aminobutyrate + urea | - |
? | |
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