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Literature summary for 3.5.3.22 extracted from

  • Elson, S.W.; Baggaley, K.H.; Davison, M.; Fulston, M.; Nicholson, N.H.; Risbridger, G.D.; Tyler, J.W.
    The identification of three new biosynthetic intermediates and one further biosynthetic enzyme in the clavulanic acid pathway (1993), J. Chem. Soc. Chem. Commun., 1993, 1212-1214.
No PubMed abstract available
Search for more literature for 3.5.3.22

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ enhances activity Streptomyces clavuligerus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
 x * 33000, SDS-PAGE Streptomyces clavuligerus

Organism

Organism UniProt Comment Textmining
Streptomyces clavuligerus
-
-
-

Reaction

Reaction Comment Organism Reaction ID
amidinoproclavaminate + H2O = proclavaminate + urea mechanism Streptomyces clavuligerus
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxyguanidinoproclavaminic acid + H2O hydrolyzed much less rapidly than guanidinoproclavamic acid Streptomyces clavuligerus deoxyproclavaminic acid + urea
-
 ?
guanidinoproclavaminic acid + H2O best substrate Streptomyces clavuligerus proclavaminic acid + urea natural product is 2S,3R enantiomer ?
guanidinoproclavaminic acid + H2O i.e. 3-hydroxy-5-guanidino-2-(2-oxoazetidin-1-yl)pentanoic acid, probably 2S,3R enantiomer Streptomyces clavuligerus proclavaminic acid + urea natural product is 2S,3R enantiomer ?
additional information no substrate: arginine Streptomyces clavuligerus ?
-
 ?

Subunits

Subunits Comment Organism
? x * 33000, SDS-PAGE Streptomyces clavuligerus