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Literature summary for 3.5.3.18 extracted from
- Roles of accumulated endogenous nitric oxide synthase inhibitors, enhanced arginase activity, and attenuated nitric oxide synthase activity in endothelial cells for pulmonary hypertension in rats (2007), Am. J. Physiol. Lung Cell Mol. Physiol., 292, L1480-L1487.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| monocrotaline | DDAH activity and DDAH1, but not DDAH2, protein expression are significantly reduced after 60mg/kg monocrotaline treatment | Rattus norvegicus |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 34000 | - |
DDAH1, SDS-PAGE | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| pulmonary artery endothelial cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| NG,NG-dimethyl-L-arginine + H2O | - |
Rattus norvegicus | dimethylamine + L-citrulline | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DDAH1 | - |
Rattus norvegicus |
| DDAH2 | - |
Rattus norvegicus |
| dimethylarginine dimethylaminohydrolase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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