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Literature summary for 3.5.3.1 extracted from

  • Hai, Y.; Edwards, J.E.; Van Zandt, M.C.; Hoffmann, K.F.; Christianson, D.W.
    Crystal structure of Schistosoma mansoni arginase, a potential drug target for the treatment of schistosomiasis (2014), Biochemistry, 53, 4671-4684.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.3.1

Inhibitors

Inhibitors Comment Organism Structure
(R)-2-amino-6-borono-2-[2-(piperidin-1-yl)ethyl]hexanoic acid
-
 Schistosoma mansoni
(R)-2-amino-6-borono-2[1-(3,4-dichlorobenzyl)piperidin-4-yl]hexanoic acid
-
 Schistosoma mansoni
2(S)-amino-6-boronohexanoic acid
-
 Schistosoma mansoni
N-hydroxyl-L-arginine
-
 Schistosoma mansoni
nor-N-hydroxy-L-arginine
-
 Schistosoma mansoni
S-(boronoethyl)-L-cysteine
-
 Schistosoma mansoni

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ contains Mn2+ Schistosoma mansoni

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-arginine + H2O Schistosoma mansoni
-
 L-ornithine + urea
-
 ?

Organism

Organism UniProt Comment Textmining
Schistosoma mansoni Q6WVP6
-
-

Source Tissue

Source Tissue Comment Organism Textmining
adult highest expression in 7 week old adult Schistosoma mansoni
-
cercaria
-
 Schistosoma mansoni
-
egg low expression Schistosoma mansoni
-
miracidium very low expression Schistosoma mansoni
-
schistosomulum highest expression in 3 h old schistosomulum Schistosoma mansoni
-
sporocyst very low expression Schistosoma mansoni
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O
-
 Schistosoma mansoni L-ornithine + urea
-
 ?

Synonyms

Synonyms Comment Organism
ARG
-
 Schistosoma mansoni