Literature summary for 3.5.3.1 extracted from

Belik, J.; Shehnaz, D.; Pan, J.; Grasemann, H.
Developmental changes in arginase expression and activity in the lung (2008), Am. J. Physiol. Lung Cell Mol. Physiol., 294, L498-L504.

Search for more literature for 3.5.3.1

Application

Application	Comment	Organism
additional information	pulmonary vascular and airway diseases in which arginase activity is increased are associated with decreased NO production and reduced smooth muscle relaxation	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
Nomega-hydroxy-nor-L-arginine	nor-NOHA; nor-NOHA	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	O08701	Sprague-Dawley rat, fetus, newborn, adult	-
Rattus norvegicus	P07824	Sprague-Dawley rat, fetus, newborn, adult	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
bronchus	-	Rattus norvegicus	-
lung	developmental changes in arginase expression and activity in the lung	Rattus norvegicus	-
additional information	arginase II is regulated developmentally, and both expression and activity are maximal during fetal life	Rattus norvegicus	-
pulmonary artery	-	Rattus norvegicus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-arginine + H2O	-	Rattus norvegicus	L-ornithine + urea	-	?

Synonyms

Synonyms	Comment	Organism
arginase	-	Rattus norvegicus
arginase I	-	Rattus norvegicus
arginase II	-	Rattus norvegicus

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Release 2023.1 (January 2023)