Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.2.9 extracted from

  • Van Der Werf, P.; Stephani, R.A.; Orlowski, M.; Meister, A.
    Inhibition of 5-oxoprolinase by 2-imidazolidone-4-carboxylic acid (1973), Proc. Natl. Acad. Sci. USA, 70, 759-761.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.2.9

Application

Application Comment Organism
medicine animal model for the human condition 5-oxoprolinuria, an inborn deficiency of renal 5-oxoprolinase activity Homo sapiens
medicine animal model for the human condition 5-oxoprolinuria, an inborn deficiency of renal 5-oxoprolinase activity Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
L-2-imidazolidone-4-carboxylate
-
 Mus musculus
L-2-imidazolidone-4-carboxylate
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-oxo-L-proline + H2O + ATP Mus musculus
-
 L-glutamate + ADP + phosphate
-
 ?
5-oxo-L-proline + H2O + ATP Homo sapiens
-
 L-glutamate + ADP + phosphate
-
 ?
5-oxo-L-proline + H2O + ATP Rattus norvegicus
-
 L-glutamate + ADP + phosphate
-
 ?
5-oxo-L-proline + H2O + ATP Rattus norvegicus Sprague-Dawley
-
 L-glutamate + ADP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 human
-
Mus musculus
-
-
-
Rattus norvegicus
-
-
-
Rattus norvegicus
-
 rat
-
Rattus norvegicus Sprague-Dawley
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Mus musculus
-
kidney
-
 Homo sapiens
-
kidney
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-oxo-L-proline + H2O + ATP
-
 Mus musculus L-glutamate + ADP + phosphate
-
 ?
5-oxo-L-proline + H2O + ATP
-
 Homo sapiens L-glutamate + ADP + phosphate
-
 ?
5-oxo-L-proline + H2O + ATP
-
 Rattus norvegicus L-glutamate + ADP + phosphate
-
 ?
5-oxo-L-proline + H2O + ATP
-
 Rattus norvegicus Sprague-Dawley L-glutamate + ADP + phosphate
-
 ?