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Literature summary for 3.5.2.6 extracted from

  • de la Prieta, M.C.; Francia, M.V.; Seoane, A.; Lobo, J.M.
    Characterization of defective beta-lactamase genes in Yersinia enterocolitica (2006), J. Antimicrob. Chemother., 58, 661-664.
    View publication on PubMed
Search for more literature for 3.5.2.6

Cloned(Commentary)

Cloned (Comment) Organism
-
 Yersinia enterocolitica

Protein Variants

Protein Variants Comment Organism
A751G inactive Yersinia enterocolitica
A751G in the ampC gene from strain Y56 the A751G mutation is responsible for the inactivation of beta-lactamase Yersinia enterocolitica
A751G mutant, inactive Yersinia enterocolitica
G984A inactive Yersinia enterocolitica
G984A mutant, inactive Yersinia enterocolitica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.01415
-
 cefalotin
-
 Yersinia enterocolitica
0.02013
-
 cefalotin
-
 Yersinia enterocolitica

Organism

Organism UniProt Comment Textmining
Yersinia enterocolitica
-
-
-
Yersinia enterocolitica
-
 strain IP97. In the bla gene from strain IP97 a deletion of 51 bp results in a completely inactive beta-lactamase. In the ampC gene from strain Y56 the A751G mutation is responsible for the inactivation of beta-lactamase
-
Yersinia enterocolitica Q01166 precursor
-
Yersinia enterocolitica IP97
-
-
-
Yersinia enterocolitica Y56 Q01166 precursor
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cefalotin + H2O
-
 Yersinia enterocolitica (2R)-5-[(acetyloxy)methyl]-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
cefalotin + H2O
-
 Yersinia enterocolitica Y56 (2R)-5-[(acetyloxy)methyl]-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
cefalotin + H2O
-
 Yersinia enterocolitica IP97 (2R)-5-[(acetyloxy)methyl]-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?

Synonyms

Synonyms Comment Organism
beta-lactamase
-
 Yersinia enterocolitica
BlaA
-
 Yersinia enterocolitica