Inhibitors | Comment | Organism | Structure |
---|---|---|---|
bulgecin A | competitive inhibition of the enzyme in its two-zinc form, but fails to inhibit when the enzyme is in the single-zinc form. The competitive inhibition is restored by restoring the second zinc ion | Bacillus cereus | |
bulgecin A | partial non-competitive inhibition | Stenotrophomonas maltophilia | |
additional information | no inhibition by bulgecin A | Aeromonas veronii |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aeromonas veronii | - |
bv. sobria | - |
Bacillus cereus | - |
- |
- |
Stenotrophomonas maltophilia | P52700 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
nitrocefin + H2O | - |
Bacillus cereus | (2R)-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-5-[(E)-2-(2,4-dinitrophenyl)ethenyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
nitrocefin + H2O | - |
Aeromonas veronii | (2R)-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-5-[(E)-2-(2,4-dinitrophenyl)ethenyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? | |
nitrocefin + H2O | - |
Stenotrophomonas maltophilia | (2R)-2-{(R)-carboxy[2-(thiophen-2-yl)acetamido]methyl}-5-[(E)-2-(2,4-dinitrophenyl)ethenyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L1 metallo-beta-lactamase | - |
Stenotrophomonas maltophilia |
metallo-beta-lactamase BceII | - |
Bacillus cereus |
metallo-beta-lactamase ImiS | - |
Aeromonas veronii |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0025 | - |
bulgecin A | 25°C, pH 7.0 | Stenotrophomonas maltophilia | |
0.23 | - |
bulgecin A | 25°C, pH 7.0 | Bacillus cereus |