Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-deoxy-4-formamido-beta-L-arabinopyranosyl undecaprenyl phosphate + H2O | Escherichia coli | because the L-Ara4N unit attached to lipid A is not derivatized with a formyl group, the existence of a deformylase, acting later in the pathway, is postulated. The requirement of the ArnA formyltransferase reaction for the maintenance of polymyxin resistance suggests that an as yet unidentified deformylase must also exist, since neither L-Ara4N-modified lipid A nor the L-Ara4N donor, undecaprenyl phosphate-L-Ara4N, is formylated when isolated from polymyxin resistant cells | 4-amino-4-deoxy-alpha-L-arabinose-undecaprenyl phosphate + formate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-deoxy-4-formamido-beta-L-arabinopyranosyl undecaprenyl phosphate + H2O | - |
Escherichia coli | 4-amino-4-deoxy-alpha-L-arabinose-undecaprenyl phosphate + formate | - |
? | |
4-deoxy-4-formamido-beta-L-arabinopyranosyl undecaprenyl phosphate + H2O | because the L-Ara4N unit attached to lipid A is not derivatized with a formyl group, the existence of a deformylase, acting later in the pathway, is postulated. The requirement of the ArnA formyltransferase reaction for the maintenance of polymyxin resistance suggests that an as yet unidentified deformylase must also exist, since neither L-Ara4N-modified lipid A nor the L-Ara4N donor, undecaprenyl phosphate-L-Ara4N, is formylated when isolated from polymyxin resistant cells | Escherichia coli | 4-amino-4-deoxy-alpha-L-arabinose-undecaprenyl phosphate + formate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
polymyxin resistance protein pmrJ | - |
Escherichia coli |
undecaprenyl-phosphate-alpha-L-Ara4FN deformylase | - |
Escherichia coli |