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Literature summary for 3.5.1.99 extracted from

  • Mukhopadhyay, P.; Horvath, B.; Rajesh, M.; Matsumoto, S.; Saito, K.; Batkai, S.; Patel, V.; Tanchian, G.; Gao, R.Y.; Cravatt, B.F.; Hasko, G.; Pacher, P.
    Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury (2011), Free Radic. Biol. Med., 50, 179-195.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.99

Protein Variants

Protein Variants Comment Organism
additional information construction of FAAH-/- mice Mus musculus

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-
Mus musculus C57/BL6J
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cardiomyocyte primary Homo sapiens
-
myocardium
-
 Mus musculus
-
myocardium
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
FAAH
-
 Mus musculus
FAAH
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction genetic deletion of FAAH is associated with enhanced acute doxorubicin-induced myocardial cell death and decreased survival, mechanism of the doxorubicin-induced myocardial cell death in FAAH+/+ and FAAH-/- mice, overview Mus musculus
metabolism fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury Mus musculus
metabolism fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury Homo sapiens
additional information anandamide induces enhanced cell death in human cardiomyocytes pretreated by FAAH inhibitor, and enhances sensitivity to reactive oxygen species generation in inflammatory cells of FAAH knockouts Homo sapiens
additional information anandamide induces enhanced cell death in human cardiomyocytes pretreated by FAAH inhibitor, and enhances sensitivity to reactive oxygen species generation in inflammatory cells of FAAH knockouts, it triggers concentration-dependent respiratory burst (ROS generation) in neutrophil granulocytes isolated from FAAH+/+ mice Mus musculus
physiological function fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury Mus musculus
physiological function fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury Homo sapiens