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Literature summary for 3.5.1.99 extracted from
- Molecular characterization of human and mouse fatty acid amide hydrolases (1997), Proc. Natl. Acad. Sci. USA, 94, 2238-2242.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Mus musculus |
| expressed in COS-7 | Rattus norvegicus |
| expressed in COS-7 | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CF3-OH | - |
Homo sapiens |  |
| CF3-OH | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Rattus norvegicus | 16020 | - |
| membrane | - |
Mus musculus | 16020 | - |
| membrane | - |
Homo sapiens | 16020 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O00519 | - |
- |
| Mus musculus | O08914 | - |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Homo sapiens | - |
| kidney | - |
Homo sapiens | - |
| liver | - |
Mus musculus | - |
| placenta | - |
Homo sapiens | - |
| skeletal muscle | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| anandamide + H2O | - |
Rattus norvegicus | ethanolamine + arachidonic acid | - |
? | |
| anandamide + H2O | - |
Homo sapiens | ethanolamine + arachidonic acid | - |
? | |
| myristic amide + H2O | 24% of the activity with anandamide | Rattus norvegicus | myristic acid + NH3 | - |
? | |
| myristic amide + H2O | 65% of the activity with anandamide | Homo sapiens | myristic acid + NH3 | - |
? | |
| oleamide + H2O | - |
Rattus norvegicus | oleic acid + NH3 | - |
? | |
| oleamide + H2O | - |
Homo sapiens | oleic acid + NH3 | - |
? | |
| palmitic amide + H2O | 10% of the activity with anandamide | Rattus norvegicus | palmitic acid + NH3 | - |
? | |
| palmitic amide + H2O | 33% of the activity with anandamide | Homo sapiens | palmitic acid + NH3 | - |
? | |
| stearic amide + H2O | 5.8% of the activity with anandamide | Rattus norvegicus | stearic acid + NH3 | - |
? | |
| stearic amide + H2O | 5.8% of the activity with anandamide | Homo sapiens | stearic acid + NH3 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| FAAH | - |
Rattus norvegicus |
| FAAH | - |
Mus musculus |
| FAAH | - |
Homo sapiens |
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