Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,1-biphenyl-3-yl-carbamic acid cyclohexyl ester | i.e. URB602 | Mus musculus | |
methyl arachidonyl fluorophosphonate | - |
Mus musculus | |
additional information | the microglial-specific isozyme is not inhibited by URB597, i.e. 3'-carbamoyl-biphenyl-3-ylcyclohexylcarbamate, and inhibitors of cyclooxygenases, lipooxygenases, and diacylglycerol lipases, overview | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-arachidonoylglycerol + H2O | Mus musculus | FAAH is responsible for approximately one-half of the 2-arachidonoylglycerol hydrolysis occurring in BV-2 cell homogenate | ? | - |
? | |
anandamide + H2O | Mus musculus | anandamide hydrolysis in BV-2 cells is entirely attributable to FAAH | ethanolamine + arachidonic acid | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
BV-2 cell | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-arachidonoylglycerol + H2O | FAAH is responsible for approximately one-half of the 2-arachidonoylglycerol hydrolysis occurring in BV-2 cell homogenate | Mus musculus | ? | - |
? | |
anandamide + H2O | anandamide hydrolysis in BV-2 cells is entirely attributable to FAAH | Mus musculus | ethanolamine + arachidonic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FAAH | - |
Mus musculus |