Activating Compound | Comment | Organism | Structure |
---|---|---|---|
cytokine IL-17 | increased expression of vanin-1 | Homo sapiens | |
cytokine IL-17 | increased expression vanin-3 | Homo sapiens | |
cytokine Th1 | increased expression of vanin-1 | Homo sapiens | |
cytokine Th1 | increased expression vanin-3 | Homo sapiens | |
additional information | 19fold upregultion of gene expression of vanin-1 psoriasis, vanin-1 expression in atopic dermatits little increased | Homo sapiens | |
additional information | 2.3fold overexpression of vanin-3 in psioriais | Homo sapiens | |
additional information | induced expression of vanin-2 in psoriasis and atopic dermatitis | Homo sapiens | |
additional information | mixture of TNF-alpha, IL-1alpha and IL-6 results in increased expression of vanin-1 in reconstructed human epidermis | Homo sapiens | |
additional information | mixture of TNF-alpha, IL-1alpha and IL-6 results in increased expression of vanin-3 in reconstructed human epidermis | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular | - |
Homo sapiens | - |
- |
membrane | membrane-bound | Homo sapiens | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pantetheine + H2O | Homo sapiens | - |
pantothenic acid + cysteamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O95497 | - |
- |
Homo sapiens | O95498 | - |
- |
Homo sapiens | Q9NY84 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
keratinocyte | - |
Homo sapiens | - |
skin | normal skin, psoriatic lesions, atopic dermatitis lesions | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pantetheine + H2O | - |
Homo sapiens | pantothenic acid + cysteamine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
pantetheinases | - |
Homo sapiens |
vanin gene family | - |
Homo sapiens |
vanin-1 | - |
Homo sapiens |
vanin-2 | - |
Homo sapiens |
vanin-3 | - |
Homo sapiens |
VNN1 | - |
Homo sapiens |
VNN2 | - |
Homo sapiens |
VNN3 | - |
Homo sapiens |