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Literature summary for 3.5.1.92 extracted from
- Enzymic hydrolysis of pantetheine (1986), Methods Enzymol., 122, 36-43.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| dithioerythritol | 1-13 mM, activates | Sus scrofa |  |
General Stability
| General Stability | Organism |
|---|---|
| after solubilization, the enzsme can be stored indefinitely in the frozen state without significant loss of activity | Sus scrofa |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Hg2+ | - |
Sus scrofa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.02 | - |
(R)-pantetheine | - |
Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 54000 | - |
gel filtration | Sus scrofa |
| 60000 | - |
1 * 60000, SDS-PAGE | Sus scrofa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | 11.8% carbohydrate by weight | Sus scrofa |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| renal cortex | - |
Sus scrofa | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 14 | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (R)-pantetheine + H2O | - |
Sus scrofa | (R)-pantothenate + cysteamine | - |
? | |
| pantothenyl-beta-aminoethanol + H2O | - |
Sus scrofa | ? | - |
? | |
| S-ethylpantetheine + H2O | - |
Sus scrofa | ? | - |
? | |
| S-pantetheine 3-pyruvate + H2O | - |
Sus scrofa | S-cysteamine 3-pyruvate + pantothenate | S-cysteamine 3-pyruvate spontaneously forms a cyclic product | ? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 60000, SDS-PAGE | Sus scrofa |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | 9.5 | - |
Sus scrofa |
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Release 2023.1 (January 2023)
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