Literature summary for 3.5.1.92 extracted from

Martin, F.; Penet, M.F.; Malergue, F.; Lepidi, H.; Dessein, A.; Galland, F.; de Reggi, M.; Naquet, P.; Gharib, B.
Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores (2004), J. Clin. Invest., 113, 591-597.

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Application

Application	Comment	Organism
medicine	the pantetheinase activity of vanin-1 molecule could be a target for a new anti-inflammatory strategy	Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Mus musculus	vanin-1-/- mice are less susceptible to intestinal inflammation, either acute or chronic. Pantetheinase activity of vanin-1 is a major regulator of intestinal inflammation, acting through cysteamine release	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	vanin-1-/- mice are less susceptible to intestinal inflammation, either acute or chronic. Pantetheinase activity of vanin-1 is a major regulator of intestinal inflammation, acting through cysteamine release	Mus musculus	?	-	?

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Release 2023.1 (January 2023)