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Literature summary for 3.5.1.9 extracted from

  • Tsuda, H.; Noguchi, T.; Kido, R.
    Formamidase in rat brain (1974), J. Neurochem., 22, 679-683.
    View publication on PubMed
Search for more literature for 3.5.1.9

Inhibitors

Inhibitors Comment Organism Structure
Ag+ complete inhibition at 0.05 mM Rattus sp.
Hg2+ 20% inhibition at 0.05 mM Rattus sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.18
-
 N-formyl-L-kynurenine
-
 Rattus sp.
0.4
-
 5-hydroxy-DL-kynurenine
-
 Rattus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5-hydroxyformyl-DL-kynurenine + H2O Rattus sp.
-
 5-hydroxy-DL-kynurenine + formate
-
 ?
N-formyl-L-kynurenine + H2O Rattus sp.
-
 L-kynurenine + formate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus sp.

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus sp.
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.8
-
-
 Rattus sp.

Storage Stability

Storage Stability Organism
0-2°C, 3 weeks Rattus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5-hydroxyformyl-DL-kynurenine + H2O
-
 Rattus sp. 5-hydroxy-DL-kynurenine + formate
-
 ?
N-formyl-L-kynurenine + H2O
-
 Rattus sp. L-kynurenine + formate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5 8.5
-
 Rattus sp.