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Literature summary for 3.5.1.88 extracted from
- Origins of the different metal preferences of Escherichia coli peptide deformylase and Bacillus thermoproteolyticus thermolysin: a comparative quantum mechanical/molecular mechanical study (2008), J. Phys. Chem. B, 112, 10280-10290.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| (S)-2-O-(phosphonoxy)-L-caproyl-L-leucyl-p-nitroanilide | - |
Escherichia coli |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Fe2+ | - |
Escherichia coli | |
| Zn2+ | - |
Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Escherichia coli | catalyzes the deformylation of nascent peptides in bacteria | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | P0A6K3 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| formyl-Met-Gly-Gly-CH3 + H2O | substrate used in QM-MM model | Escherichia coli | formate + Met-Gly-Gly-CH3 | - |
? | |
| additional information | catalyzes the deformylation of nascent peptides in bacteria | Escherichia coli | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| peptide deformylase | - |
Escherichia coli |
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Release 2023.1 (January 2023)
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