Literature summary for 3.5.1.88 extracted from

Shen, G.; Zhu, J.; Simpson, A.M.; Pei, D.
Design and synthesis of macrocyclic peptidyl hydroxamates as peptide deformylase inhibitors (2008), Bioorg. Med. Chem. Lett., 18, 3060-3063.

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Inhibitors

Inhibitors	Comment	Organism	Structure
2-[(12R,17aS)-1,13-dioxohexadecahydro-1H-pyrrolo[1,2-a][1,4]diazacyclopentadecin-12-yl]-N-hydroxyacetamide	-	Escherichia coli
2-[(3S,6R)-3-tert-butyl-2,5-dioxo-1,4-diazacyclopentadecan-6-yl]-N-hydroxyacetamide	-	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
N-formyl-Met-Leu-p-nitroanilide + H2O	-	Escherichia coli	formate + Met-Leu-p-nitroanilide	-	?

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Release 2023.1 (January 2023)