Application | Comment | Organism |
---|---|---|
medicine | target for antibacterial agents against Staphylococcus aureus | Staphylococcus aureus |
Cloned (Comment) | Organism |
---|---|
for expession in Escherichia coli C41(DE3) cells with a C-terminal eight-residue, LEHHHHHH, tag | Staphylococcus aureus |
Crystallization (Comment) | Organism |
---|---|
crystal structure of Staphylococcus aureus peptide deformylase, SaPDF, in complex with its inhibitor actinonin at 1.9 A resolution | Staphylococcus aureus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
actinonin | - |
Staphylococcus aureus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Zn2+ | - |
Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
formyl-L-methionyl peptide + H2O | Staphylococcus aureus | - |
formate + methionyl peptide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
purified by two chromatographic steps involving affinity and gel filtration columns | Staphylococcus aureus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
formyl-L-methionyl peptide + H2O | - |
Staphylococcus aureus | formate + methionyl peptide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
- |
Staphylococcus aureus | |
peptide deformylase | - |
Staphylococcus aureus |
SaPDF | - |
Staphylococcus aureus |