Any feedback?
Literature summary for 3.5.1.88 extracted from
- Role of the metal ion in formyl-peptide bond hydrolysis by a peptide deformylase active site model (2006), J. Phys. Chem. B, 110, 1063-1072.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | peptide deformylase may be a potential target for designing new antibiotics | Escherichia coli |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | - |
Escherichia coli |  |
| Cu2+ | - |
Escherichia coli | |
| Fe2+ | - |
Escherichia coli | |
| Ni2+ | - |
Escherichia coli | |
| Zn2+ | - |
Escherichia coli | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| formyl-L-methionyl peptide + H2O | Escherichia coli | - |
formate + methionyl peptide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
- |
- |
Oxidation Stability
| Oxidation Stability | Organism |
|---|---|
| Fe2+-containing peptide deformylase is very unstable because of its sensibility toward environmental oxygen | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| formyl-L-methionyl peptide + H2O | - |
Escherichia coli | formate + methionyl peptide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
- |
Escherichia coli | |
| peptide deformylase | - |
Escherichia coli |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
