Literature summary for 3.5.1.88 extracted from

Kumar, A.; Nguyen, K.T.; Srivathsan, S.; Ornstein, B.; Turley, S.; Hirsh, I.; Pei, D.; Hol, W.G.J.
Crystals of peptide deformylase from Plasmodium falciparum reveal critical characteristics of the active site for drug design (2002), Structure, 10, 357-367.

Search for more literature for 3.5.1.88

Application

Application	Comment	Organism
medicine	the enzyme is a potential antibacterial and antimalarial drug target	Plasmodium falciparum

Cloned(Commentary)

Cloned (Comment)	Organism
-	Plasmodium falciparum
expression in Escherichia coli	Plasmodium falciparum

Crystallization (Commentary)

Crystallization (Comment)	Organism
sitting-drop vapour-diffusion method, crystals grown from either native or SeMet-substituted protein, 2.8 A resolution with ten subunits per asymmetric unit	Plasmodium falciparum
unusual type of noncrystallographic symmetry	Plasmodium falciparum

Organism

Organism	UniProt	Comment	Textmining
Plasmodium falciparum	-	-	-
Plasmodium falciparum	-	enzyme form 1 and 2	-

Purification (Commentary)

Purification (Comment)	Organism
-	Plasmodium falciparum

Synonyms

Synonyms	Comment	Organism
Pf PDF	-	Plasmodium falciparum

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Release 2023.1 (January 2023)