Literature summary for 3.5.1.84 extracted from

Karns, J.S.; Eaton, R.W.
Genes encoding s-triazine degradation are plasmid-borne in Klebsiella pneumoniae strain 99 (1997), J. Agric. Food Chem., 45, 1017-1022.

Search for more literature for 3.5.1.84

Application

Application	Comment	Organism
agriculture	one step in the mineralization of s-triazine compounds, extensive used as herbicides or pesticides in agriculture worldwide, and hence in their complete removal from environment	Klebsiella pneumoniae

Cloned(Commentary)

Cloned (Comment)	Organism
strain 99, cloning large conjugal plasmid pPDL12, carrying the genes encoding the s-triazine degradation pathway, including the trzE gene encoding biuret amidohydrolase in Klebsiella planticola ATCC 33531, expression in Klebsiella planticola ATCC 33531	Klebsiella pneumoniae

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
biuret + H2O	Klebsiella pneumoniae	imidodicarbonic diamide	urea + CO2 + NH3	-	?
biuret + H2O	Klebsiella pneumoniae	involved in metabolism of s-triazine ring structure, component of several important herbicides, including atrazine	urea + CO2 + NH3	-	?
biuret + H2O	Klebsiella pneumoniae	involved in a pathway by which herbicides based on the symmetrical triazine ring, s-triazine, including atrazine, 2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine, are degraded in bacteria	urea + CO2 + NH3	-	?
biuret + H2O	Klebsiella pneumoniae	second enzyme of degradative pathway of cyanuric acid	urea + CO2 + NH3	-	?

Organism

Organism	UniProt	Comment	Textmining
Klebsiella pneumoniae	-	wild-type and mutants	-
Klebsiella pneumoniae 99	-	wild-type and mutants	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
biuret + H2O	imidodicarbonic diamide	Klebsiella pneumoniae	urea + CO2 + NH3	-	?
biuret + H2O	involved in metabolism of s-triazine ring structure, component of several important herbicides, including atrazine	Klebsiella pneumoniae	urea + CO2 + NH3	-	?
biuret + H2O	involved in a pathway by which herbicides based on the symmetrical triazine ring, s-triazine, including atrazine, 2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine, are degraded in bacteria	Klebsiella pneumoniae	urea + CO2 + NH3	-	?
biuret + H2O	second enzyme of degradative pathway of cyanuric acid	Klebsiella pneumoniae	urea + CO2 + NH3	-	?

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Release 2023.1 (January 2023)