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Literature summary for 3.5.1.6 extracted from

  • Thomas, H.R.; Ezzeldin, H.H.; Guarcello, V.; Mattison, L.K.; Fridley, B.L.; Diasio, R.B.
    Genetic regulation of beta-ureidopropionase and its possible implication in altered uracil catabolism (2008), Pharmacogenet. Genomics, 18, 25-35.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
mutation A85E is introduced into the wild-type UPB1 plasmid using site-directed mutagenesis. The mutated plasmid is then transfected into the RKO cell line Homo sapiens

Protein Variants

Protein Variants Comment Organism
A85E expression of the A85E plasmid results in severely reduced BUP-1 enzyme activity, with only 2.7% activity relative to the wild-type UPB1 plasmid Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
BUP-1
-
Homo sapiens