Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.5.1.42 extracted from

  • Hillyard, D.; Rechsteiner, M.; Manlapaz-Ramos, P.; Imperial, J.S.; Cruz, L.J.; Olivera, B.M.
    The pyridine nucleotide cycle. Studies in Escherichia coli and the human cell line D98/AH2 (1981), J. Biol. Chem., 256, 8491-8497.
    View publication on PubMed
Search for more literature for 3.5.1.42

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.014
-
 beta-nicotinamide D-ribonucleotide
-
 Escherichia coli

Localization

Localization Comment Organism GeneOntology No. Textmining
intracellular
-
 Escherichia coli 5622
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
beta-nicotinamide D-ribonucleotide + H2O Escherichia coli contribution to the recycling pathway of NAD+ beta-nicotinate D-ribonucleotide + NH3
-
 ?
beta-nicotinamide D-ribonucleotide + H2O Homo sapiens contribution to the recycling pathway of NAD+ beta-nicotinate D-ribonucleotide + NH3
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
near homogeneity, chromatography techniques Escherichia coli

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Escherichia coli
-
cell culture
-
 Homo sapiens
-
HeLa cell
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2900
-
-
 Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
beta-nicotinamide D-ribonucleotide + H2O
-
 Escherichia coli beta-nicotinate D-ribonucleotide + NH3
-
 ?
beta-nicotinamide D-ribonucleotide + H2O
-
 Homo sapiens beta-nicotinate D-ribonucleotide + NH3
-
 ?
beta-nicotinamide D-ribonucleotide + H2O contribution to the recycling pathway of NAD+ Escherichia coli beta-nicotinate D-ribonucleotide + NH3
-
 ?
beta-nicotinamide D-ribonucleotide + H2O contribution to the recycling pathway of NAD+ Homo sapiens beta-nicotinate D-ribonucleotide + NH3
-
 ?

pH Range

pH Minimum pH Maximum Comment Organism
5
-
 no activity below Escherichia coli