Literature summary for 3.5.1.30 extracted from

Park, S.J.; Kim, E.Y.; Noh, W.; Park, H.M.; Oh, Y.H.; Lee, S.H.; Song, B.K.; Jegal, J.; Lee, S.Y.
Metabolic engineering of Escherichia coli for the production of 5-aminovalerate and glutarate as C5 platform chemicals (2013), Metab. Eng., 16, 42-47.

Cloned(Commentary)

Cloned (Comment)	Organism
gene davA, functional recombinant expression in Escherichia coli strains WL3110 and XQ56 from vector pKE112-MCS, co-expression with gene davB from Pseudomnas putida, encoding lysine 2-monooxygenase, as well as with gabTD genes encoding 5AVA aminotransferase and glutarate semialdehyde dehydrogenase, addition of L-lysine and 2-oxoglutarate results in synthesis of 5-aminovalerate and glutrate, overview	Pseudomonas putida

Cloned (Comment)

Organism

gene davA, functional recombinant expression in Escherichia coli strains WL3110 and XQ56 from vector pKE112-MCS, co-expression with gene davB from Pseudomnas putida, encoding lysine 2-monooxygenase, as well as with gabTD genes encoding 5AVA aminotransferase and glutarate semialdehyde dehydrogenase, addition of L-lysine and 2-oxoglutarate results in synthesis of 5-aminovalerate and glutrate, overview

Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
5-aminopentanamide + H2O	Pseudomonas putida	-	5-aminopentanoate + NH3	-	r
5-aminopentanamide + H2O	Pseudomonas putida ATCC 12633	-	5-aminopentanoate + NH3	-	r

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas putida	B3IVI7	-	-
Pseudomonas putida ATCC 12633	B3IVI7	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
5-aminopentanamide + H2O	-	Pseudomonas putida	5-aminopentanoate + NH3	-	r
5-aminopentanamide + H2O	-	Pseudomonas putida ATCC 12633	5-aminopentanoate + NH3	-	r

Synonyms

Synonyms	Comment	Organism
delta-aminovaleramidase	-	Pseudomonas putida

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Release 2023.1 (January 2023)