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Literature summary for 3.5.1.26 extracted from
- Glycoasparaginase in human urine (1991), Biochim. Biophys. Acta, 1097, 28-30.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | diagnosis of aspartylglycosaminuria in urine samples | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.09 | - |
N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine | - |
Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| extracellular | - |
Homo sapiens | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 18000 | - |
heavy-chain2, 2 * 25000 + light-chain2, 2 * 18000, SDS-PAGE | Homo sapiens |
| 25000 | - |
heavy-chain2, 2 * 25000 + light-chain2, 2 * 18000, SDS-PAGE | Homo sapiens |
| 80000 | - |
non-denaturing PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O | Homo sapiens | - |
2-acetamido-1-amino-1,2-dideoxy-beta-D-glucose + L-aspartate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| to homogeneity, chromatography techniques | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| urine | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 3 | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| N4-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H2O | - |
Homo sapiens | 2-acetamido-1-amino-1,2-dideoxy-beta-D-glucose + L-aspartate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | heavy-chain2, 2 * 25000 + light-chain2, 2 * 18000, SDS-PAGE | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glycoasparaginase | - |
Homo sapiens |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | - |
95% loss of activity within 60 min | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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