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Literature summary for 3.5.1.24 extracted from

  • Smith, K.; Zeng, X.; Lin, J.
    Discovery of bile salt hydrolase inhibitors using an efficient high-throughput screening system (2014), PLoS ONE, 9, e85344.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.5.1.24

Inhibitors

Inhibitors Comment Organism Structure
caffeic acid phenethyl ester 99.7% inhibition at 5 mM Ligilactobacillus salivarius
carnosic acid 96.8% inhibition at 5 mM Ligilactobacillus salivarius
cephradine
-
 Ligilactobacillus salivarius
chrysophanol 3.7% inhibition at 1.25 mM Ligilactobacillus salivarius
Cloxacillin
-
 Ligilactobacillus salivarius
demeclocycline 92.0% inhibition at 5 mM Ligilactobacillus salivarius
doxycycline 92.9% inhibition at 5 mM Ligilactobacillus salivarius
epicatechin monogallate 98.6% inhibition at 5 mM Ligilactobacillus salivarius
erythromycin 36.5% inhibition at 5 mM Ligilactobacillus salivarius
gossypetin 97.3% inhibition at 5 mM Ligilactobacillus salivarius
Lincomycin 67.3% inhibition at 5 mM Ligilactobacillus salivarius
menadione 87.2% inhibition at 5 mM Ligilactobacillus salivarius
methacycline 90.2% inhibition at 5 mM Ligilactobacillus salivarius
additional information identification of bile salt hydrolase inhibitors using an efficient high-throughput screening system, method optimization, overview; no inhibition by folic acid at 1.5 mM and bacitracin at 5 mM Ligilactobacillus salivarius
oxytetracycline 97.4% inhibition at 5 mM Ligilactobacillus salivarius
purpurogallin 83.0% inhibition at 5 mM Ligilactobacillus salivarius
riboflavin 99.3% inhibition at 1 mM Ligilactobacillus salivarius
roxarsone 98.4% inhibition at 5 mM Ligilactobacillus salivarius
streptomycin
-
 Ligilactobacillus salivarius
sulfamethazine 48.7% inhibition at 5 mM Ligilactobacillus salivarius
theaflavanin 18.1% inhibition at 5 mM Ligilactobacillus salivarius
tylosin 23.8% inhibition at 5 mM Ligilactobacillus salivarius

Organism

Organism UniProt Comment Textmining
Ligilactobacillus salivarius
-
 isolated from chicken
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glycocholic acid + H2O
-
 Ligilactobacillus salivarius cholate + glycine
-
 ?
taurodeoxycholic acid + H2O
-
 Ligilactobacillus salivarius deoxycholate + taurine
-
 ?

Synonyms

Synonyms Comment Organism
bile salt hydrolase
-
 Ligilactobacillus salivarius
BSH
-
 Ligilactobacillus salivarius

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Ligilactobacillus salivarius

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 assay at Ligilactobacillus salivarius