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Literature summary for 3.5.1.23 extracted from

  • Wu, J.X.; Li, J.; Liu, Z.; Yin, J.; Chang, Z.Y.; Rong, C.; Wu, J.L.; Bi, F.C.; Yao, N.
    The Arabidopsis ceramidase AtACER functions in disease resistance and salt tolerance (2015), Plant J., 81, 767-780.
    View publication on PubMed
Search for more literature for 3.5.1.23

Cloned(Commentary)

Cloned (Comment) Organism
gene At4G22330 or acer-1, phylogenetic analysis, recombinant expression of GFP-tagged enzyme in Arabidopsis thaliana Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of an acer-1 T-DNA insertion mutant, the acer-1 allele has a T-DNA insertion in the 50 untranslated region (5'-UTR) of AtACER, phenotype with reduced stature, with smaller, narrower, glossier leaves and smaller flowers than wild-type plants, sphingolipid profiles in acer-1, overview. The AtACER transgene can complement the phenotypes of the acer-1 mutant Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
endoplasmic reticulum the enzyme localizes predominantly to the endoplasmic reticulum, and partially to the Golgi complex Arabidopsis thaliana 5783
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Golgi apparatus the enzyme localizes predominantly to the endoplasmic reticulum, and partially to the Golgi complex Arabidopsis thaliana 5794
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additional information subcellular localization study, expression analysis, overview Arabidopsis thaliana
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Metals/Ions

Metals/Ions Comment Organism Structure
NaCl at 150 mM NaCl, acer-1 seedlings dramatically loose vitality compared with the wild-type, the amiR-ACER-1 seedlings are the most sensitive to salt, showing obvious differences from the other genotypes after 100 mM NaCl treatment for 12 days Arabidopsis thaliana

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q94IB9 gene acer-1 or At4G22330
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Source Tissue

Source Tissue Comment Organism Textmining
leaf low in mature leaves Arabidopsis thaliana
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meristem shoot Arabidopsis thaliana
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additional information tissue localization study, expression analysis, overview Arabidopsis thaliana
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pollen
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 Arabidopsis thaliana
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root
-
 Arabidopsis thaliana
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shoot
-
 Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
alkaline ceramidase
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 Arabidopsis thaliana
AtACER
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 Arabidopsis thaliana

General Information

General Information Comment Organism
evolution phylogenetic analysis of alkaline ceramidases Arabidopsis thaliana
malfunction the acer-1 T-DNA insertion mutant has pleiotropic phenotypes, including reduction of leaf size, dwarfing and an irregular wax layer, compared with wild-type plants, higher level of phytoceramides in acer-1 and amiR-ACER-1 plants than in the wild-type, phenotype, overview. Acer-1 mutants and AtACER RNAi lines show increased sensitivity to salt stress, and lines overexpressing AtACER show increased tolerance to salt stress. Reduction of AtACER also increases plant susceptibility to Pseudomonas syringae Arabidopsis thaliana
metabolism key biological functions of ceramidases in biotic and abiotic stresses in plants Arabidopsis thaliana
physiological function the enzyme is involved in salt tolerance and in disease resistance Arabidopsis thaliana