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Literature summary for 3.5.1.23 extracted from

  • Eliyahu, E.; Shtraizent, N.; Martinuzzi, K.; Barritt, J.; He, X.; Wei, H.; Chaubal, S.; Copperman, A.B.; Schuchman, E.H.
    Acid ceramidase improves the quality of oocytes and embryos and the outcome of in vitro fertilization (2010), FASEB J., 24, 1229-1238.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
cumulus cell
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Homo sapiens
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follicular fluid
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Homo sapiens
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oocyte acid ceramidase is an essential component of the in vivo oocyte and embryo environment, it is expressed in the cortex and membrane at all stages of human oocyte maturation, expression analysis, overview Homo sapiens
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Synonyms

Synonyms Comment Organism
acid ceramidase
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Homo sapiens

General Information

General Information Comment Organism
physiological function acid ceramidase improves the quality of oocytes and embryos and the outcome of in vitro fertilization, the level of the enzyme is positively correlated with the quality of human embryos formed in vitro. Addition of recombinant acid ceramidase to human oocyte culture medium maintains the healthy cell morphology in vitro Homo sapiens