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Literature summary for 3.5.1.23 extracted from
- Population genetic analysis of the N-acylsphingosine amidohydrolase gene associated with mental activity in humans (2008), Genetics, 178, 1505-1515.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | ASAH1 hydrolyzes ceramides and regulates neuronal development, and its deficiency often results in mental retardation. Results of linkage disequilibrium and polymorphism analyses suggest that a particular group of haplotypes in ASAH1 represents a signature of recent positive Darwinian selection | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | ASAH1 hydrolyzes ceramides and regulates neuronal development, and its deficiency often results in mental retardation. Results of linkage disequilibrium and polymorphism analyses suggest that a particular group of haplotypes in ASAH1 represents a signature of recent positive Darwinian selection | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ASAH1 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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