Literature summary for 3.5.1.23 extracted from

Saad, A.F.; Meacham, W.D.; Bai, A.; Anelli, V.; Elojeimy, S.; Mahdy, A.E.; Turner, L.S.; Cheng, J.; Bielawska, A.; Bielawski, J.; Keane, T.E.; Obeid, L.M.; Hannun, Y.A.; Norris, J.S.; Liu, X.
The functional effects of acid ceramidase overexpression in prostate cancer progression and resistance to chemotherapy (2007), Cancer Biol. Ther., 6, 1455-1460.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
DU-145 cell	acid ceramidase is closely associated with malignant progression in human prostate cancer tissues. Acid ceramidase upregulation generates tumor cells that are resistant to normal homeostatic control mechanisms, have an increased number of metastatic characteristics and exhibit resistance to chemotherapy	Homo sapiens	-
PPC-1 cell	acid ceramidase is closely associated with malignant progression in human prostate cancer tissues. Acid ceramidase upregulation generates tumor cells that are resistant to normal homeostatic control mechanisms, have an increased number of metastatic characteristics and exhibit resistance to chemotherapy	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
acid ceramidase	-	Homo sapiens

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Release 2023.1 (January 2023)