Cloned (Comment) | Organism |
---|---|
expression of the N-terminally GFP-tagged enzyme lacking the 19 amino acid N-terminal extension in HEK-293 and MCF7 cells exclusively in mitohcondria, expression of the longer enzyme version cloned from kidney resulted in localization of the recombinant enzyme in the plasma membrane of HEK-293 cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | subcellular localization, overview | Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NR71 | N-CDase | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-nitrobenzo-2-oxa-1,3-diazole-C12-ceramide + H2O | - |
Homo sapiens | 4-nitrobenzo-2-oxa-1,3-diazole-dodecanoic acid + ceramide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CDase | - |
Homo sapiens |
N-CDase | - |
Homo sapiens |
neutral ceramidase | - |
Homo sapiens |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Homo sapiens |