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Literature summary for 3.5.1.22 extracted from

  • Nurmikko, V.; Salo, E.; Hakkola, H.; Maekinen, K.; Snell, E.E.
    The bacterial degradation of pantothenic acid. II. pantothenate hydrolase (1966), Biochemistry, 5, 399-403.
    View publication on PubMed
Search for more literature for 3.5.1.22

Inhibitors

Inhibitors Comment Organism Structure
dieethyldithiocarbamate 10 mM, 36% inhibition Pseudomonas fluorescens
EDTA 10 mM, 45% inhibition Pseudomonas fluorescens
KCN 10 mM, 42% inhibition Pseudomonas fluorescens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5
-
 pantothenic acid P-2, pH 7.4 at 28°C Pseudomonas fluorescens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
pantothenic acid + H2O Pseudomonas fluorescens
-
 ?
-
 ?
pantothenic acid + H2O Pseudomonas fluorescens P-2
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas fluorescens
-
 P-2
-
Pseudomonas fluorescens P-2
-
 P-2
-

Purification (Commentary)

Purification (Comment) Organism
-
 Pseudomonas fluorescens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
pantothenic acid + H2O
-
 Pseudomonas fluorescens beta-alanine + D-pantoyl lactone + H2O
-
 r
pantothenic acid + H2O
-
 Pseudomonas fluorescens P-2 beta-alanine + D-pantoyl lactone + H2O
-
 r
pantothenic acid + H2O
-
 Pseudomonas fluorescens ?
-
 ?
pantothenic acid + H2O
-
 Pseudomonas fluorescens P-2 ?
-
 ?

Synonyms

Synonyms Comment Organism
pantothenate hydrolase
-
 Pseudomonas fluorescens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
28 29 above 30°C denaturation of enzyme Pseudomonas fluorescens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 strain P-2 Pseudomonas fluorescens