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Literature summary for 3.5.1.20 extracted from
- L-Citrulline (1985), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 8, 412-418.
No PubMed abstract available
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | clinical biochemistry, therapeutic measurement of citrulline | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-citrulline + H2O | Homo sapiens | enzyme is specific for citrulline, no hydrolysis of arginine, argininosuccinate, or other guanidino compounds | ? | - |
? |  |
| L-citrulline + H2O | Homo sapiens | first intermediate in urea cycle, involved in arginine biosynthesis | ? | - |
? | |
| L-citrulline + H2O | Tetrahymena sp. | first intermediate in urea cycle, involved in arginine biosynthesis | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
| Tetrahymena sp. | - |
protozoan | - |
| Tetrahymena sp. | - |
thermophila, pyryformis | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Tetrahymena sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| citrulline + H2O | - |
Homo sapiens | ornithine + CO2 + NH3 | - |
? | |
| citrulline + H2O | - |
Tetrahymena sp. | ornithine + CO2 + NH3 | - |
? | |
| L-citrulline + H2O | enzyme is specific for citrulline, no hydrolysis of arginine, argininosuccinate, or other guanidino compounds | Homo sapiens | ? | - |
? | |
| L-citrulline + H2O | first intermediate in urea cycle, involved in arginine biosynthesis | Homo sapiens | ? | - |
? | |
| L-citrulline + H2O | first intermediate in urea cycle, involved in arginine biosynthesis | Tetrahymena sp. | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| citrulline hydrolase | - |
Tetrahymena sp. |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | 37 | - |
Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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