Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P45470 | - |
- |
Homo sapiens | Q99497 | - |
- |
Pyrococcus furiosus | Q51732 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O | - |
Pyrococcus furiosus | a [protein]-L-arginine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O | - |
Homo sapiens | a [protein]-L-arginine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-arginine + H2O | - |
Escherichia coli | a [protein]-L-arginine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-cysteine + H2O | - |
Pyrococcus furiosus | a [protein]-L-cysteine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-cysteine + H2O | - |
Homo sapiens | a [protein]-L-cysteine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-cysteine + H2O | - |
Escherichia coli | a [protein]-L-cysteine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O | - |
Pyrococcus furiosus | a [protein]-L-lysine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O | - |
Homo sapiens | a [protein]-L-lysine + (R)-lactate | - |
? | |
an S-(1-hydroxy-2-oxopropyl)-[protein]-L-lysine + H2O | - |
Escherichia coli | a [protein]-L-lysine + (R)-lactate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
deglycase | - |
Pyrococcus furiosus |
deglycase | - |
Homo sapiens |
deglycase | - |
Escherichia coli |
DJ-1 | - |
Homo sapiens |
Maillard deglycase | - |
Pyrococcus furiosus |
Maillard deglycase | - |
Homo sapiens |
Maillard deglycase | - |
Escherichia coli |
PARK7 | - |
Homo sapiens |
PfpI | - |
Pyrococcus furiosus |
yhbO | - |
Escherichia coli |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
assay at | Homo sapiens |
70 | - |
assay at | Escherichia coli |
70 | - |
assay at, deglycase activity | Pyrococcus furiosus |
Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | 95 | enzyme activity is reduced by 72% for YhbO 70°C, YhbO is inactive at 95°C | Escherichia coli |
55 | 95 | enzyme activity is reduced by 74% for DJ-1 at 70°C, DJ-1 is inactive at 95°C | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Pyrococcus furiosus |
7 | - |
assay at | Homo sapiens |
7 | - |
assay at | Escherichia coli |
General Information | Comment | Organism |
---|---|---|
evolution | the enzyme PfpI belongs to the PfpI/Hsp31/DJ-1 superfamily | Pyrococcus furiosus |
physiological function | the enzyme prevents acrylamide formation in vivo, acrylamide formation in the glyoxal/asparagine mixture is reduced by 72% by PfpI | Pyrococcus furiosus |
physiological function | the enzyme prevents acrylamide formation in vivo, acrylamide formation in the glyoxal/asparagine mixture is reduced by 78% by YhbO | Escherichia coli |
physiological function | the enzyme prevents acrylamide formation in vivo, acrylamide formation in the glyoxal/asparagine mixture is reduced by 98% by DJ-1 | Homo sapiens |