Any feedback?
Literature summary for 3.5.1.12 extracted from
- Biotinidase in the porcine cerebrum (1990), Arch. Biochem. Biophys., 278, 381-385.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| diisopropylfluorophosphate | - |
Rattus rattus |  |
| diisopropylfluorophosphate | no inhibition of biotinidase from brain | Sus scrofa | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | - |
Cavia porcellus | 5737 | - |
| cytoplasm | - |
Homo sapiens | 5737 | - |
| cytoplasm | - |
Sus scrofa | 5737 | - |
| cytoplasm | - |
Oryctolagus cuniculus | 5737 | - |
| cytoplasm | - |
Rattus rattus | 5737 | - |
| microsome | - |
Cavia porcellus | - |
- |
| microsome | - |
Rattus rattus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 68000 | - |
- |
Homo sapiens |
| 68000 | - |
SDS-PAGE | Sus scrofa |
| 70000 | - |
gel permeation, nondenaturating | Sus scrofa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| biotin amide + H2O | Cavia porcellus | - |
? | - |
? | |
| biotin amide + H2O | Homo sapiens | - |
? | - |
? | |
| biotin amide + H2O | Sus scrofa | - |
? | - |
? | |
| biotin amide + H2O | Oryctolagus cuniculus | - |
? | - |
? | |
| biotin amide + H2O | Rattus rattus | - |
? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | Cavia porcellus | - |
? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | Homo sapiens | - |
? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | Sus scrofa | - |
? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | Rattus rattus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
guinea pig | - |
| Homo sapiens | - |
human | - |
| Oryctolagus cuniculus | - |
rabbit | - |
| Rattus rattus | - |
rat | - |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Cavia porcellus | - |
| brain | - |
Homo sapiens | - |
| brain | - |
Oryctolagus cuniculus | - |
| brain | - |
Rattus rattus | - |
| brain | cerebrum, cerebellum, medulla | Sus scrofa | - |
| liver | - |
Cavia porcellus | - |
| liver | - |
Homo sapiens | - |
| liver | - |
Sus scrofa | - |
| liver | - |
Rattus rattus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| biotin amide + H2O | - |
Cavia porcellus | ? | - |
? | |
| biotin amide + H2O | - |
Homo sapiens | ? | - |
? | |
| biotin amide + H2O | - |
Sus scrofa | ? | - |
? | |
| biotin amide + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| biotin amide + H2O | - |
Rattus rattus | ? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Cavia porcellus | biotin + L-lysine | - |
ir | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Homo sapiens | biotin + L-lysine | - |
ir | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Sus scrofa | biotin + L-lysine | - |
ir | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Oryctolagus cuniculus | biotin + L-lysine | - |
ir | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Rattus rattus | biotin + L-lysine | - |
ir | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Cavia porcellus | ? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Homo sapiens | ? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Sus scrofa | ? | - |
? | |
| epsilon-N-biotinyl-L-lysine + H2O | - |
Rattus rattus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 68000, SDS-PAGE | Homo sapiens |
| monomer | 1 * 68000, SDS-PAGE | Sus scrofa |
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